I.V. GLYCERYL TRINITRATE: HAEMODYNAMIC EFFECTS AND CLINICAL USE IN CARDIAC SURGERY
نویسندگان
چکیده
منابع مشابه
I.V. glyceryl trinitrate: haemodynamic effects and clinical use in cardiac surgery.
A commercial preparation of glyceryl trinitrate for i.v. administration was assessed under both experimental and clinical conditions. The overall haemodynamic effects were beneficial during coronary artery grafting and aortic valve replacement, when the drug was given at a rate of 0.8 microgram kg-1 min-1 at which dose there was no appreciable effect on resistance vessels. No adverse side-effec...
متن کاملHaemodynamic effects of hydrallazine and of hydrallazine plus glyceryl trinitrate paste in heart failure.
In a study designed to investigate potential non-parenteral treatment for chronic heart failure, hydrallazine, 225 to 300 mg per day, was given orally to 9 patients. There was no significant change in heart rate or mean arterial pressure as cardiac output increased. Left ventricular stroke work increased significantly and pulmonary artery wedge pressure fell. Systemic and pulmonary vascular res...
متن کاملComparison of haemodynamic effects of phentolamine, sodium nitroprusside, and glyceryl trinitrate in acute myocardial infarction.
The effects of the commonly employed systemic vasodilators phentolamine, nitroprusside, and intravenous glyceryl trinitrate on cardiac performance, peripheral resistance, and vascular capacitance, as judged by changes in left ventricular filling pressure, were compared in 29 patients studied within 24 hours after the onset of acute myocardial infarction. To provide a common basis for comparison...
متن کاملPotential deleterious haemodynamic effects of glyceryl trinitrate on myocardial ischaemia in man.
The potential adverse effects of glyceryl trinitrate on myocardial ischaemia were studied using low and high dose infusions in 10 patients with coronary heart disease. Cardiac venous flow was measured by the thermodilution technique and blood was sampled for metabolic studies. Angina pectoris was provoked by atrial pacing before drug infusion and the same heart rate was regained with low and hi...
متن کاملHaemodynamic effects of glyceryl trinitrate during continuous 24 hour infusion in patients with heart failure.
OBJECTIVE To investigate whether the susceptibility to tolerance to glyceryl trinitrate is similar in different vascular beds in patients with chronic heart failure. PATIENTS Twenty patients with heart failure underwent a continuous infusion of glyceryl trinitrate over 24 hours followed by administration of N-acetylcysteine (5 g intravenously) in a bolus. MAIN OUTCOME MEASURES Haemodynamic ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: British Journal of Anaesthesia
سال: 1982
ISSN: 0007-0912
DOI: 10.1093/bja/54.3.297